故事发生在很久很久以前,乍得(杰克·布莱克 饰)和奥尔(迈克尔·塞拉 饰)是一个原始部落中的猎人。两人因为不遵守部落中的规矩而被驱逐,于是两人互相为伴,踏上了离群的旅程。沿途他们遇见了亚当和夏娃、该隐和亚伯、亚伯拉罕等一系列圣经人物,亲眼见证了一系列圣经故事的发生。最后,他们来到了传说中的罪恶之城索多玛,然而这个地方在他们看来简直宛如天堂,于是也注定了这个地方成为他们旅途的终点……Zed, a prehistoric would-be hunter, eats from a tree of forbidden fruit and is banished from his tribe, accompanied by Oh, a shy gatherer. On their travels, they meet Cain and Abel on a fateful day, stop Abraham from killing Isaac, become slaves, and reach the city of Sodom where their tribe is now enslaved. Zed and Oh are determined to rescue the women they love, Maya and Eema. Standing in their way is Sodom's high priest and the omnipresent Cain. Zed tries to form an alliance with Princess Innana, which may backfire. Can an inept hunter and a smart but slender and diffident gatherer become heroes and make a difference?