飓风正在侵袭美国新奥尔良，一位病危的老妇睁开了她的睡眼。老妇名叫戴茜（凯特·布兰切特饰），她叫女儿凯若琳（朱莉娅•奥蒙德饰）为她阅读一本日记。这本日记的作者叫本杰明•巴顿（布拉德•皮特饰）。本杰明出生在第一次世界大战停战之时，但生来便像个老人的他被父亲当作怪物，被遗弃在了养老院。本杰明在养老院与老人们一起生活。但谁都没有想到，本杰明逆向发育——越活越年轻！也许“越活越年轻”是某些人的梦想，但真正这样成长的本杰明却有了别人无法理解的烦恼与快乐。穿越半世纪的世界变革，本杰明身处其中，感受别人感受不到的感受。 为何母亲会让自己念这本日记？本杰明•巴顿此人与母亲有什么关系？凯若琳陷入了深深的疑惑与好奇之中。On the day that Hurricane Katrina hits New Orleans, elderly Daisy Williams (nee Fuller) is on her deathbed in a New Orleans hospital. At her side is her adult daughter, Caroline. Daisy asks Caroline to read to her aloud the diary of Daisy's lifelong friend, Benjamin Button. Benjamin's diary recounts his entire extraordinary life, the primary unusual aspect of which was his aging backwards, being diagnosed with several aging diseases at birth and thus given little chance of survival, but who does survive and gets younger with time. Abandoned by his biological father, Thomas Button, after Benjamin's biological mother died in childbirth, Benjamin was raised by Queenie, a black woman and caregiver at a seniors home. Daisy's grandmother was a resident at that home, which is where she first met Benjamin. Although separated through the years, Daisy and Benjamin remain in contact throughout their lives, reconnecting in their forties when in age they finally match up. Some of the revelations in Benjamin's diary are difficult for Caroline to read, especially as it relates to the time past this reconnection between Benjamin and Daisy, when Daisy gets older and Benjamin grows younger into his childhood years.
